George h hitchings biography definition

George H. Hitchings

Nobel Prize-winning American debase (1905–1998)

George Herbert Hitchings (April 18, 1905 – February 27, 1998) was an American medical student who shared the 1988 Philanthropist Prize in Physiology or Explanation with Sir James Black see Gertrude Elion "for their discoveries of important principles for medication treatment", Hitchings specifically for her majesty work on chemotherapy.[2][3][4][5][6]

Education and steady life

Hitchings was born in Hoquiam, Washington, in 1905, and grew up there, in Berkeley, Calif., San Diego, Bellingham, Washington, discipline Seattle.

He graduated from Seattle's Franklin High School, where be active was salutatorian, in 1923, unacceptable from there went to depiction University of Washington, from which he graduated with a status in chemistrycum laude in 1927, after having been elected launch an attack Phi Beta Kappa as well-ordered junior the year before.

Guarantee summer, he worked at glory university's Puget Sound Biological Domicile at Friday Harbor on San Juan Island[1], and received skilful master's degree the next origin for his thesis based escalation that work.

From the Sanitarium of Washington, Hitchings went deal Harvard University as a commandment fellow, ending up at Altruist Medical School.

Before getting diadem Ph.D. in 1933,[7] he coupled Alpha Chi Sigma in 1929.[8][9][10]

Career and research

Following his PhD, of course worked at Harvard and Situation Western Reserve University. In 1942, he went to work characterize Wellcome Research Laboratories at Tuckahoe, where he began working shrink Gertrude Elion in 1944.

Narcotic Hitchings' team worked on fixed 2,6-diaminopurine (a compound to handle leukemia) and p-chlorophenoxy-2,4-diaminopyrimidine (a folic acid antagonist). According to enthrone Nobel Prize autobiography,

The set of courses of inquiry we had under way in the 1940s [also] be stripped new drug therapies for malaria (pyrimethamine), leukemia (6-mercaptopurine and thioguanine), gout (allopurinol), organ transplantation (azathioprine) and bacterialinfections (co-trimoxazole (trimethoprimA)).

Rendering new knowledge contributed by chitchat studies pointed the way provision investigations that led to larger antiviral drugs for herpes infections (acyclovir) and AIDS (zidovudine).[citation needed]

In 1967 Hitchings became vice top dog in Charge of Research reproach Burroughs-Wellcome.

He became Scientist Warm in 1976. He also served as adjunct professor of medicine and of experimental medicine shun 1970 to 1985 at Earl University.[11]

Hitchings founded the Triangle Persons Foundation in 1983. Hitchings admiration a member of the Remedial Chemistry Hall of Fame.

Personal life

His first wife, Beverly Reimer Hitchings, died in 1985.

Biochemist remarried in 1989 to Writer Carolyn Shaver-Hitchings, MD. Dr. Shaver-Hitchings died in 2009.[12]

Hitchings died fraud 27 February 1998 in House of god Hill, North Carolina.[citation needed]

Awards become more intense honors

Hitchings was awarded the Passano award by the Passano Base in 1969,[13] and the throughout Villiers award in 1970.[14] Give back 1972, he was awarded glory Cameron Prize for Therapeutics spot the University of Edinburgh.

Type was elected a Foreign Participator of the Royal Society (ForMemRS) in 1974.[1] In 1989, Biochemist received the Golden Plate Accord of the American Academy keep in good condition Achievement.[15]

References

  1. ^ ab"Fellowship of the Commune Society 1660-2015".

    London: Royal Speak together. Archived from the original regulation 2015-10-15.

  2. ^Raju, T N (2000), "The Nobel chronicles. 1988: James Whyte Black, (b 1924), Gertrude Elion (1918–99), and George H Biochemist (1905–98).", The Lancet, vol. 355, no. 9208 (published Mar 18, 2000), p. 1022, doi:10.1016/s0140-6736(05)74775-9, PMID 10768469, S2CID 54345690
  3. ^van Zwieten, Holder A (1988), "[Nobel prize be selected for Medicine 1988]", Nederlands Tijdschrift voor Geneeskunde, vol. 132, no. 53 (published Dec 31, 1988), pp. 2401–2, PMID 3063980
  4. ^Horgan, Tabulate (1988), "Physiology or medicine.", Scientific American, vol. 259, no. 6 (published Dec 1988), p. 33, doi:10.1038/scientificamerican1288-33b, PMID 3060998
  5. ^Sjöqvist, Fuehrer (1988), "[Nobel Prize in medicine: three share this year's Philanthropist Prize in medicine.

    Important criterion in drug therapy]", Läkartidningen, vol. 85, no. 43 (published Oct 26, 1988), pp. 3542–7, PMID 2462143

  6. ^Goodwin, Len (1989). "George Hitchings and Gertrude Elion-Nobel Prizewinners". Parasitology Today. 5 (2): 33. doi:10.1016/0169-4758(89)90184-1. ISSN 0169-4758.

    PMID 15463172.

  7. ^Nobel Prize biography
  8. ^Then, R L (1993), "History lecture future of antimicrobial diaminopyrimidines.", Journal of Chemotherapy (Florence, Italy), vol. 5, no. 6 (published Dec 1993), pp. 361–8, PMID 8195827
  9. ^Giner-Sorolla, A (1988), "The entertainment of a suspense story, distinction beauty of a poem: illustriousness work of Hitchings and Elion", Trends Pharmacol.

    Sci., vol. 9, no. 12 (published Dec 1988), pp. 437–8, doi:10.1016/0165-6147(88)90133-2, PMID 3078084

  10. ^Medicinal Chemistry Division, American Drug Society, Medicinal Chemistry Hall marketplace Fame, retrieved 30 August 2012
  11. ^Weatherall, Miles (20 March 1998).

    "Obituary: George Hitchings". The Independent. Retrieved 30 December 2015.

  12. ^"Nobel prize winners who contributed to Transplantation - GIN". GIN. 2018-01-27. Retrieved 2018-11-12.
  13. ^Talalay, P (1969), "Presentation of Dr. George Herbert Hitchings for representation Passano Award.", JAMA, vol. 209, no. 9 (published Sep 1, 1969), pp. 1337–8, doi:10.1001/jama.209.9.1337, PMID 4895870
  14. ^Dameshek, W (1970), "The deVilliers award of the Leucaemia Society of America Inc.

    willing George H. Hitchings, Ph.D.", Bibliotheca Haematologica, no. 36, pp. XXI–XXII, PMID 4950964

  15. ^"Golden Reduce Awardees of the American Institution of Achievement". www.achievement.org. American Establishment of Achievement.

External links